In Spider-Man 2, Mysteriums are unique challenges scattered throughout the game where players can earn medals based on their performance. Each Mysterium has its own set of requirements and objectives, making them a test of both skill and strategy.

These challenges not only offer an engaging way to sharpen your Spider-Man abilities but also reward you with Hero Tokens for stellar performances. However, the game doesn't readily disclose the locations of each challenge. This guide will help you find all 10 mysteriums.

Location	Mysterium	Gold	Silver	Bronze
Harlem	Under Construction	<1:00	<1:30	>1:30
Central Park	Everyone’s a Critic	<1:45	<2:15	>2:15
Upper East Side	Prison Break	<2:15	<2:45	>2:45
Midtown	The Invisible Enemy	<2:10	<2:40	>2:40
Chinatown	Fight on Time	<3:30	<5:00	>5:00
Williamsburg	Road Rage	0	<3	>3
Williamsburg	Grave Decision	0	<3	>3
Downtown Brooklyn	Fear of Heights	<1:30	<2:15	>2:15
Downtown Queens	Punch Your Ticket	<2:00	<3:20	3:20
Downtown Brooklyn	Grand Finale	-	-	-

1. Harlem's "Under Construction" Mysterium

This is a “defeat all enemies”-style challenge. However, there's a twist: around halfway through the challenge, poison gas will fill the arena, constantly draining your health. You can heal to recover, but if you’re on a good pace and have upgraded your health, then you should concentrate on using your Focus for finishers to complete the challenge faster.

Located in Harlem, players are tasked with defeating 20 enemies in under a minute.

• Central Start: Initiating the challenge from the middle provides a panoramic view of the entire area, allowing for quick target acquisition and efficient movement.
• Web Grabber Gadget: This tool is not just for pulling enemies closer; it disrupts their formations, making it easier to isolate and defeat them.
• Clockwise Movement: A systematic clockwise approach ensures no enemy is overlooked, providing a flow to the combat.
• Mist Alert: The mist not only damages Spider-Man but can obscure vision. Quick reflexes and constant movement are key to avoiding its harmful effects.
• AOE Abilities: Using abilities that affect multiple enemies simultaneously can drastically reduce the time taken to clear the area.

2. Central Park's "Everyone's a Critic" Mysterium

This challenge focuses on beating a number of enemies quickly. The twist here is that partway through, Mysterio himself will show up and give all the enemies a buff that makes them invulnerable to damage. You should focus only on Mysterio floating around to remove the buff as fast as you can, allowing you to finish off the remaining grunts.

Situated in Central Park, players have 1 minute and 45 seconds to defeat 30 enemies.

• Pure Skill: This challenge is straightforward, relying heavily on the player's combat proficiency. Quick combos, dodges, and aerial moves can be highly effective.
• Web Grabber: The gadget's ability to pull enemies closer means you can string together combos more efficiently, reducing the time between takedowns.

3. Upper East Side's "Prison Break" Mysterium

This challenge is essentially a big brawl against waves of enemies. Your goal is to clear them out as quickly as possible.

In the Upper East Side, players must defeat 20 enemies within 2 minutes and 15 seconds while some enemies are shielded.

• Mysterio Priority: Shielded enemies can't be damaged. Locating and defeating Mysterio quickly will disable these shields, making the enemies vulnerable.
• Mobility: Constant movement prevents being cornered by shielded enemies, allowing for hit-and-run tactics.
• Web Grabber: The gadget can be used to break enemy formations, making it easier to target Mysterio among the crowd.

4. Midtown's "The Invisible Enemy" Mysterium

In this challenge, you need to beat enemies quickly. There are two twists: firstly, you need to perform finishers to make the KO count, and secondly, enemies become invisible after a short time. However, this doesn't mean they're invulnerable. A great trick here is to use your Gadget that pulls all enemies together, making any enemies around you visible and vulnerable to attack.

In Midtown, players are challenged to use six finishers within 2 minutes and 10 seconds.

• Finisher Focus: Building up the focus bar quickly is essential. Maintaining a high combo count by dodging and attacking successively can speed up this process.
• Agility: Quick dodges and aerial maneuvers can help in avoiding enemy attacks, ensuring the combo count remains high.
• Web Grabber: Invisible enemies can be a challenge. The gadget can reveal them, making it easier to target and defeat them.

5. Chinatown's "Fight On Time" Mysterium

This is another take on the Finisher challenge. You'll be fighting under a large clock. After set intervals, the clock will shoot a tracking beam at you that you need to avoid. It won’t instantly kill you, but it does a lot of damage and interrupts anything you were doing.

In Chinatown, the objective is to kick 15 enemies off rooftops within 1 minute and 30 seconds.

• Avoid Laser: Avoid laser when the clock strikes 12. This way, you can use your focus on finishing moves instead of healing.
• Jump Kicks: A well-timed jump followed by an attack can send enemies flying off rooftops. It's essential to get the angle and timing right.
• Web Grabber: Aiming this gadget off the building's side can pull enemies into a free fall, counting towards the objective.

6. Williamsburg's "Grave Decision" Mysterium

This challenge is similar to Road Rage but takes place in a graveyard. The objective remains the same: don't get hit. However, Mysterio himself will show up around halfway through to add even more chaos to the equation.

The first Williamsburg challenge requires players to defeat waves of enemies without taking a single hit.

• Constant Movement: Staying stationary makes you an easy target. Continuously moving, swinging, and jumping can make it difficult for enemies to land a hit.
• AOE Attacks: Abilities that can target multiple enemies simultaneously can clear out groups quickly, reducing the chances of getting hit.
• Train Track Awareness: The glowing green train tracks are a hazard. Being aware of their location and timing can prevent accidental hits.

7. Williamsburg's "Road Rage" Mysterium

This challenge has you fighting on a bridge, with a few floating islands nearby, as enemies and traffic spawn in. Your goal is to take out all the enemies while taking as few hits as possible. Each hit will add a point to your score, so the lower your score, the better. Be cautious of shooters and lanes of traffic on the bridge that light up, indicating an incoming car.

The second Williamsburg challenge tasks players with defeating 20 enemies without getting hit, all while dodging moving cars.

• Positioning: Staying on the edges of the streets or on rooftops can reduce the risk of getting hit by cars.
• AOE Attacks: Clearing groups of enemies quickly can reduce the chaos and make it easier to dodge both enemies and cars.
• Web Swinging: Using web swings to stay airborne can be an effective way to avoid ground-based threats.

8. Downtown Brooklyn's "Fear of Heights" Mysterium

Positioned on a rooftop, your task is to knock the specified number of enemies off the edge as quickly as you can. The most efficient way to do this is to spam your swing kick move, which launches enemies up and away better than any other move.

In Downtown Brooklyn, players must kick 15 enemies off rooftops within a set time.

• Kick : This tool can be used strategically to pull enemies towards the edge, setting them up for a kick off the building.
• Awareness: Being conscious of your position relative to the edge of the building can make it easier to execute kicks that send enemies plummeting.

9. Downtown Queens' "Punch Your Ticket" Mysterium

Your challenge here is to eliminate a number of Brute enemies specifically, though other enemies will appear as well. A train will occasionally spawn and drive through the arena wherever you happen to be at the time. You get a good amount of warning by seeing the green tracks before the train itself comes, which you need to use to your advantage to bait Brutes into the tracks for easy KOs.

In Downtown Queens, players are challenged to defeat six brute-type enemies within 2 minutes.

• Brute Priority: These enemies are tougher and can take more damage. Focusing on them first can make the challenge more manageable.
• Finishers: Using finishers on brutes can quickly reduce their health, speeding up their defeat.
• Mobility: Brutes are powerful but slow. Using agility to dodge their attacks and counterattacking can be an effective strategy.

10. Downtown Brooklyn's "Grand Finale" Mysterium

Once all other challenges are complete, you get one last mission to wrap up this story and get to the bottom of this little mystery once and for all. This is more of a boss battle and not a challenge, so there are no medals or time requirements. Finishing this quest also unlocks the Smoke and Mirrors Suit for Miles.

The final challenge in Downtown Brooklyn is a unique boss fight.

• Combination of Skills: This challenge tests everything learned throughout the game. Using a mix of dodges, attacks, gadgets, and finishers can be the key to success.
• AOE Attacks: When facing multiple enemies, using attacks that target multiple foes can be beneficial.
• Dodge and Counter: Staying agile and countering enemy attacks can turn the tide of the battle.

For those of you tracking down every secret in Spider-Man 2, find all the rare tech crate locations to upgrade your gear, then swing over to collect each of the 42 spider bots scattered across the city. To make sure you're hitting every milestone, check out the full mission list, which will help you keep track of your progress alongside the quest for all mysterium locations.